Loading
If this is the first time anyone has visited this substance, we may be fetching live data from TGA Product Information, PBS, and state framework sources — that can take up to a minute. Cached substances load in a second or two.
Vancomycin is a glycopeptide antibiotic medication used to treat certain bacterial infections. It is administered intravenously (injection into a vein) to treat complicated skin infections, bloodstream infections, endocarditis, bone and joint infections, and meningitis caused by methicillin-resistant Staphylococcus aureus. Blood levels may be measured to determine the correct dose. Vancomycin is also taken orally (by mouth) to treat Clostridioides difficile infections. When taken orally, it is poorly absorbed.
Read the full article on WikipediaInfection Clinical criteria: The treatment must be initiated in a hospital, AND The condition must be one in which vancomycin is an appropriate antibiotic.
Endocarditis Clinical criteria: The treatment must be for prophylaxis, AND Patient must be hypersensitive to penicillin.
Antibiotic associated pseudomembranous colitis Clinical criteria: The condition must be due to Clostridium difficile, AND The condition must be unresponsive to metronidazole.
“Vancomycin targets bacterial cell wall synthesis by binding to the basic building block of the bacterial cell wall of Gram-positive bacteria, whether it is of aerobic or anaerobic type. Specifically, vancomycin forms hydrogen bonds with the D-alanyl-D-alanine (D-Ala-D-Ala) peptide motif of the peptidoglycan precursor, a component of the bacterial cell wall.”
“4 h to 11 h (adults, normal renal function)6 d to 10 d (adults, impaired renal function)”
Working under the parallel aged-care framework? Aged-care equivalent →