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Curated subset. The full adverse-effect list is in the TGA Product Information; click any citation above to open it.
“Antithrombin III, an alpha2-glycoprotein of molecular weight 58,000 daltons, is normally present in human plasma at a concentration of approximately 12.5 mg/dL and is the major plasma inhibitor of thrombin. Inactivation of thrombin by ATIII occurs by formation of a covalent bond resulting in an inactive 1:1 stoichiometric complex between the active serine of thrombin and an arginine reactive site of ATIII.”
“The half-life (t½) of ATIII was 3.2 days based on immunological assays and 2.8 days based on functional assays of ATIII.”
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