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Hyperphosphataemia Clinical criteria: Treatment Phase: Initiation and stabilisation The condition must not be adequately controlled by calcium, AND Patient must have a serum phosphate of greater than 1.6 mmol per L at the commencement of therapy; OR The condition must be where a serum calcium times phosphate product is greater than 4 at the commencement of therapy, AND The treatment must not be used in combination with any other non-calcium phosphate binding agents. Treatment criteria: Patient must be undergoing dialysis for chronic kidney disease.
“Sevelamer Waymade contains sevelamer, a non-absorbed phosphate binding poly(allylamine hydrochloride) polymer, free of metal and calcium. It contains multiple amines separated by one carbon from the polymer backbone. These amines become partially protonated in the intestine and interact with phosphorus molecules through ionic and hydrogen bonding. By binding phosphorus in the dietary tract, sevelamer lowers the phosphorus concentration in the serum.”
Working under the parallel aged-care framework? Aged-care equivalent →
Curated subset. The full adverse-effect list is in the TGA Product Information; click any citation above to open it.