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Sevelamer (rINN) is a phosphate binding medication used to treat hyperphosphatemia in patients with chronic kidney disease. When taken with meals, it binds to dietary phosphate and prevents its absorption. Sevelamer was invented and developed by GelTex Pharmaceuticals. Sevelamer is marketed by Sanofi under the brand names Renagel (sevelamer hydrochloride) and Renvela (sevelamer carbonate).
Read the full article on WikipediaHyperphosphataemia Clinical criteria: Treatment Phase: Initiation and stabilisation The condition must not be adequately controlled by calcium, AND Patient must have a serum phosphate of greater than 1.6 mmol per L at the commencement of therapy; OR The condition must be where a serum calcium times phosphate product is greater than 4 at the commencement of therapy, AND The treatment must not be used in combination with any other non-calcium phosphate binding agents. Treatment criteria: Patient must be undergoing dialysis for chronic kidney disease.
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