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Mycobacterium avium complex infection Clinical criteria: Patient must be human immunodeficiency virus (HIV) positive.
“Rifabutin has activity in vitro against laboratory strains and clinical isolates of M. tuberculosis.”
“The t 1/2 β of Mycobutin in humans is approximately 35-40 hours.”
“Therefore, as rifabutin has been shown to induce the enzymes of the cytochrome P450 3A subfamily, treatment may affect the pharmacokinetic behaviour of drugs metabolised by the enzymes belonging to that subfamily (as is seen with rifampicin).”
Working under the parallel aged-care framework? Aged-care equivalent →
Curated subset. The full adverse-effect list is in the TGA Product Information; click any citation above to open it.