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“Propranolol hydrochloride is a β-adrenoreceptor blocking agent which acts non-selectively on β- receptors (β1 and β2).”
With chronic administration the mean plasma half-life is from 3 – 6 hours, determined by clearance and plasma binding. The plasma half-life of oral propranolol is of the order of 3 – 6 hours.↗TGA PIT1✓
“Pharmacokinetic studies have shown that the following agents may interact with propranolol due to effects on enzyme systems in the liver which metabolise propranolol and these agents: quinidine, rifampicin, theophylline, warfarin, thioridazine and dihydropyridine calcium channel blockers such as nifedipine, nisoldipine, and isradipine.”
Curated subset. The full adverse-effect list is in the TGA Product Information; click any citation above to open it.