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Curated subset. The full adverse-effect list is in the TGA Product Information; click any citation above to open it.
“After topical application of methyl aminolevulinate, during the 3 hours under occlusion, porphyrins will accumulate intracellulary in the treated skin lesions. The intracellular porphyrins (including PpIX) are photoactive, fluorescing compounds and, upon light activation in the presence of oxygen, singlet oxygen is formed which causes damage to cellular compartments, in particular the mitochondria.”