Metaraminol, also known as metaradrine and sold under the brand name Aramine among others, is a sympathomimetic medication which is used in the prevention and treatment of hypotension (low blood pressure), particularly as a complication of anesthesia. It is given by intramuscular or intravenous administration.
Read the full article on Wikipedia“The dominant mechanism of action for the vasopressor action of metaraminol is indirect, with metaraminol displacing norepinephrine from neuronal vesicles in order for the noradrenaline to exert these effects. Metaraminol at higher doses may have direct α-adrenergic agonist and β1-adrenergic agonist effects. However at doses common in clinical practice, the indirect α1-adrenergic effects predominate, such that reflex bradycardia is a common side effect.”
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