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Idiopathic menorrhagia Clinical criteria: The treatment must be in a patient where oral treatments are ineffective.
“Levonorgestrel is a progestogen. The precise mode of action of Norlevo-1 is not known. Emergency hormonal contraception is thought to work mainly by preventing ovulation and fertilisation by altering tubal transport of sperm and/or ova.”
“After oral administration of 1.5 mg levonorgestrel (two 750 microgram tablets as a single dose), the plasma terminal half-life of the product is estimated to 43 hours.”
“The metabolism of levonorgestrel can be enhanced by concomitant use of drugs which induce CYP3A4, one of the family of liver enzymes.”