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For prescribing by certain health practitioners Clinical criteria: Treatment criteria: Must be treated by a health practitioner who is any of: (i) a medical practitioner, (ii) an authorised PBS prescriber who is not a medical practitioner, but who is: (a) sharing care of the patient with at least one medical practitioner; (b) intending to share care of the patient with a medical practitioner.
“Isoniazid is tuberculostatic agent. It has antibacterial activity only against mycobacteria. It has bacteriostatic activity against Mycobacterium tuberculosis and is one of the first line chemotherapeutic agents used in treating tuberculosis.”
“The plasma half-life of isoniazid in patients with normal renal and hepatic function ranges from 1 to 4 hours, depending on the rate of metabolism.”
Working under the parallel aged-care framework? Aged-care equivalent →
Curated subset. The full adverse-effect list is in the TGA Product Information; click any citation above to open it.
“Isoniazid is thought to induce cytochrome P450 that results in an increased proportion of paracetamol being converted to toxic metabolites.”