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Curated subset. The full adverse-effect list is in the TGA Product Information; click any citation above to open it.
“Interferons bind to specific receptors on the cell surface initiating a complex intracellular signalling pathway and rapid activation of gene transcription. Interferon-stimulated genes modulate many biological effects including the inhibition of viral replication in infected cells, inhibition of cell proliferation, and immunomodulation.”
“After IV administration, the terminal half-life of peginterferon alfa-2a in healthy subjects is approximately 60 h compared to 3 – 4 h for standard interferon. A mean elimination half-life of 160 h (84 – 353 h) at primary elimination phase was observed in patients after subcutaneous (SC) administration of Pegasys.”
Working under the parallel aged-care framework? Aged-care equivalent →