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“It is a DNA intercalating agent which reacts with topoisomerase II and has an inhibitory effect on nucleic acid synthesis.”
“Estimates of the plasma half-life for the parent compound range from 10 to 35 hours. Idarubicin is extensively metabolized to an active metabolite, idarubicinol, which has a plasma half-life ranging from 41 to 69 hours.”
Curated subset. The full adverse-effect list is in the TGA Product Information; click any citation above to open it.