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Severe pain Clinical criteria: The treatment must be for short term therapy of acute severe pain, AND Patient must have had or would have inadequate pain management with maximum tolerated doses of non-opioid and other opioid analgesics; OR Patient must be unable to use non-opioid and other opioid analgesics due to contraindications or intolerance.
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“Hydromorphone is an opioid agonist with no antagonist activity.”
“Following intravenous administration of hydromorphone to normal volunteers, the mean half- life of elimination was 2.64 ± 0.88 hours.”
Curated subset. The full adverse-effect list is in the TGA Product Information; click any citation above to open it.