Loading
If this is the first time anyone has visited this substance, we may be fetching live data from TGA Product Information, PBS, and state framework sources — that can take up to a minute. Cached substances load in a second or two.
Hydrochlorothiazide, sold under the brand name Hydrodiuril among others, is a diuretic medication used to treat hypertension and swelling due to fluid build-up. Other uses include treating diabetes insipidus and renal tubular acidosis and to decrease the risk of kidney stones in hypercalciuria. Hydrochlorothiazide is taken by mouth and may be combined with other blood pressure medications as a single pill to increase effectiveness. Hydrochlorothiazide is a thiazide medication which inhibits reabsorption of sodium and chloride ions from the distal convoluted tubules of the kidneys, causing a natriuresis. This initially increases urine volume and lowers blood volume. It is believed to reduce peripheral vascular resistance.
Read the full article on Wikipedia“Hydrochlorothiazide inhibits the sodium-chloride cotransporter in the distal convoluted tubules, which normally reabsorb 5–10% of sodium. This increases sodium delivery to the collecting ducts and reduces sodium-potassium ATPase activity, limiting sodium and water reabsorption.”
“5.6–14.8 h”
Working under the parallel aged-care framework? Aged-care equivalent →