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Gadobutrol (INN; Gd-DO3A-butrol) is a gadolinium-based MRI contrast agent (GBCA). It received marketing approval in Canada and the United States. As of 2007, it was the only GBCA approved at 1.0 molar concentrations.
Read the full article on Wikipedia“Gadobutrol is a paramagnetic macrocyclic contrast agent administered intravenously for use in magnetic resonance imaging. The contrast-enhancing effect is a result of the neutral complex of gadolinium and dihydroxy-hydroxymethylpropyl-tetraazacyclododecane-triacetic acid (butrol), which works to decrease differences in longitudinal relaxation times (T1) and differences in spin-spin or transverse relaxation times (T2). These relaxation times, coupled with differences in proton density, are responsible for the variation in intensity of radio frequency signals which contribute to an MRI's tissue visualization capabilities. Greater signal enhancement, and therefore, greater tissue visualization, is achieved with increased shortening of T1 and T2.”
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