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Curated subset. The full adverse-effect list is in the TGA Product Information; click any citation above to open it.
“Fosfomycin inhibits the first stage of bacterial wall synthesis. It inhibits the phosphoenolpyruvate transferase enzyme, thereby irreversibly blocking the condensation of uridine diphosphate-N- acetylglucosamine with p-enolpyruvate.”
“Fosfomycin is excreted unchanged mainly via the kidneys by glomerular filtration (40-50% of the dose is found in the urine) with an elimination half-life of about 4 hours and to a lesser extent in faeces (18-28% of the dose).”
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