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“Oral administration of fexofenadine to guinea pigs, indicated that fexofenadine antagonised histamine-induced skin wheals in a dose-dependent manner.”
“The plasma concentration vs. time profiles of fexofenadine follow a bi-exponential decline with a mean terminal elimination half-life ranging from 14 to 15 hours following multiple dosing.”
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Curated subset. The full adverse-effect list is in the TGA Product Information; click any citation above to open it.
“As fexofenadine undergoes negligible hepatic biotransformation, it is unlikely to interact with other drugs through hepatic metabolism.”