Loading
If this is the first time anyone has visited this substance, we may be fetching live data from TGA Product Information, PBS, and state framework sources — that can take up to a minute. Cached substances load in a second or two.
Major depressive disorders Clinical criteria: The condition must be stable for the prescriber to consider the listed maximum quantity of this medicine suitable for this patient.
Select your state to see jurisdictional framework, reporting obligations, and authority links. Substance information above is the same in every state.
“Duloxetine is a selective serotonin and noradrenaline reuptake inhibitor, and weakly inhibits dopamine uptake with no significant affinity for histaminergic, dopaminergic, cholinergic and adrenergic receptors.”
“The half-life of duloxetine (unchanged drug) is 12.1 hours.”
“Both CYP2D6 and CYP1A2 catalyse the formation of the initial oxidation steps to form 4-, 5-, and 6-hydroxy duloxetine.”
Curated subset. The full adverse-effect list is in the TGA Product Information; click any citation above to open it.