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Major depressive disorders Clinical criteria: The condition must be stable for the prescriber to consider the listed maximum quantity of this medicine suitable for this patient.
“Duloxetine is a selective serotonin and noradrenaline reuptake inhibitor, and weakly inhibits dopamine uptake with no significant affinity for histaminergic, dopaminergic, cholinergic and adrenergic receptors.”
“The half-life of duloxetine (unchanged drug) is 12.1 hours.”
“Both CYP2D6 and CYP1A2 catalyse the formation of the initial oxidation steps to form 4-, 5-, and 6-hydroxy duloxetine.”
Working under the parallel aged-care framework? Aged-care equivalent →
Curated subset. The full adverse-effect list is in the TGA Product Information; click any citation above to open it.