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Curated subset. The full adverse-effect list is in the TGA Product Information; click any citation above to open it.
“Anti- inflammatory actions, such as blocking the inflammatory cell influx and inhibition of inflammatory mediator release by inhibition of the arachidonic acid pathway, are probably important. The intrinsic potency of budesonide, measured as affinity to the glucocorticoid receptor, is about 15 times higher than that of prednisolone.”
“Excretion of budesonide given as ENTOCORT modified release capsules is rate limited by its absorption, and the terminal half-life averages 4 hours.”
“The metabolism of budesonide is primarily mediated by CYP3A4, a subfamily of cytochrome P450.”