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Osteoarthritis Clinical criteria: The treatment must be for symptomatic treatment.
Rheumatoid arthritis Clinical criteria: The treatment must be for symptomatic treatment.
“The mechanism of action of celecoxib is believed to be due to inhibition of prostaglandin synthesis, primarily by inhibition of COX-2.”
“At steady state the elimination half- life (t1/2) was 4-15 hours and the clearance was about 500 mL/min.”
“In-vitro and in-vivo studies indicate that metabolism is mainly by cytochrome P450 CYP 2C9 (see section 4.5 Interactions with other medicines and other forms of interactions).”
Working under the parallel aged-care framework? Aged-care equivalent →
Curated subset. The full adverse-effect list is in the TGA Product Information; click any citation above to open it.