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Curated subset. The full adverse-effect list is in the TGA Product Information; click any citation above to open it.
“Brimonidine tartrate is an alpha-2 adrenergic agonist that is 1000-fold more selective for the alpha-2 adrenoreceptor than the alpha-1 adrenergic receptor.”
“The mean apparent half-life in the systemic circulation was approximately 2 hours in humans after topical dosing.”
“As brimonidine is metabolised primarily by the liver, most likely by cytochrome P450 and aldehyde oxidase, this may affect the metabolism of other drugs that utilise the cytochrome P450 pathway.”
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