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Moderate to severe heart failure Clinical criteria: The condition must be stable for the prescriber to consider the listed maximum quantity of this medicine suitable for this patient, AND Patient must be stabilised on conventional therapy, which must include an ACE inhibitor or Angiotensin II antagonist, if tolerated.
“Bisoprolol is a β1-selective-adrenoceptor blocking agent, lacking intrinsic stimulating and relevant membrane stabilising activity.”
“Bisoprolol has an elimination half-life of 10-12 hours.”
“In vitro data from studies in human liver microsomes show that bisoprolol is primarily metabolized via CYP3A4 (~ 95%) with CYP2D6 having only a minor role.”
Working under the parallel aged-care framework? Aged-care equivalent →
Curated subset. The full adverse-effect list is in the TGA Product Information; click any citation above to open it.