Loading
If this is the first time anyone has visited this substance, we may be fetching live data from TGA Product Information, PBS, and state framework sources — that can take up to a minute. Cached substances load in a second or two.
Parkinson disease Clinical criteria: Patient must have experienced severely disabling motor fluctuations which have not responded to other therapy, AND The treatment must be commenced in a specialist unit in a hospital setting.
“Apomorphine is a directly acting dopamine receptor agonist, structurally related to dopamine.”
“The elimination half -life (t1/2) is about 33 minutes.”
“Routes of metabolism in humans include sulfation, N- demethylation, glucuronidation and oxidation to norapomorphine by CYP 2B6, CYP 2C8 and CYP 3A4.”
Working under the parallel aged-care framework? Aged-care equivalent →
Curated subset. The full adverse-effect list is in the TGA Product Information; click any citation above to open it.