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Diabetic macular oedema (DMO) Clinical criteria: Treatment Phase: Initial treatment Patient must have visual impairment due to diabetic macular oedema, AND Patient must have documented visual impairment defined as a best corrected visual acuity score between 78 and 39 letters based on the early treatment diabetic retinopathy study chart administered at a distance of 4 metres (approximate Snellen equivalent 20/32 to 20/160), in the eye proposed for treatment, AND The condition must be diagnosed by optical coherence tomography; OR The condition must be diagnosed by fluorescein angiography, AND The treatment must be as monotherapy; OR The treatment must be in combination with laser photocoagulation, AND The treatment must be the sole PBS-subsidised therapy for this condition. Treatment criteria: Must be treated by an ophthalmologist or by an accredited ophthalmology registrar in consultation with an ophthalmologist. Authority approval for initial treatment of each eye must be sought. Details (date, unique identifying number/code or provider number) of one of the following diagnostic reports for each eye must be documented in the patient's medical records: (i) fluorescein angiogram report; (ii) optical coherence tomography report.
Branch retinal vein occlusion with macular oedema Clinical criteria: Treatment Phase: Initial treatment Treatment criteria: Must be treated by an ophthalmologist or by an accredited ophthalmology registrar in consultation with an ophthalmologist. Patient must have visual impairment due to macular oedema secondary to branched retinal vein occlusion (BRVO), AND Patient must have documented visual impairment defined as a best corrected visual acuity score between 73 and 20 letters based on the early treatment diabetic retinopathy study chart administered at a distance of 4 metres (approximate Snellen equivalent 20/40 to 20/400), in the eye proposed for treatment, AND The condition must be diagnosed by optical coherence tomography; OR The condition must be diagnosed by fluorescein angiography, AND The treatment must be the sole PBS-subsidised therapy for this condition. Authority approval for initial treatment of each eye must be sought. The first authority application for each eye must be made via the Online PBS Authorities System (real time assessment) or in writing via HPOS form upload or mail and must include: (1) Details (date, unique identifying number/code or provider number) of the optical coherence tomography or fluorescein angiogram report. If the application is submitted through HPOS form upload or mail, it must include: (a) details of the proposed prescription; and (b) a completed authority application form relevant to the indication and treatment phase (the latest version is located on the website specified in the Administrative Advice). All reports must be documented in the patient's medical records.
“Aflibercept acts as a soluble decoy receptor that binds VEGF-A and PlGF with higher affinity than their natural receptors, and thereby can inhibit the binding and activation of these cognate VEGF receptors.”
Working under the parallel aged-care framework? Aged-care equivalent →
Central retinal vein occlusion with macular oedema Clinical criteria: Treatment Phase: Initial treatment Treatment criteria: Must be treated by an ophthalmologist or by an accredited ophthalmology registrar in consultation with an ophthalmologist. Patient must have visual impairment due to macular oedema secondary to central retinal vein occlusion (CRVO), AND Patient must have documented visual impairment defined as a best corrected visual acuity score between 73 and 24 letters based on the early treatment diabetic retinopathy study chart administered at a distance of 4 metres (approximate Snellen equivalent 20/40 to 20/320), in the eye proposed for treatment, AND The condition must be diagnosed by optical coherence tomography; OR The condition must be diagnosed by fluorescein angiography, AND The treatment must be the sole PBS-subsidised therapy for this condition. Authority approval for initial treatment of each eye must be sought. The first authority application for each eye must be made via the Online PBS Authorities System (real time assessment) or in writing via HPOS form upload or mail and must include: (1) Details (date, unique identifying number/code or provider number) of the optical coherence tomography or fluorescein angiogram report. If the application is submitted through HPOS form upload or mail, it must include: (a) details of the proposed prescription; and (b) a completed authority application form relevant to the indication and treatment phase (the latest version is located on the website specified in the Administrative Advice). All reports must be documented in the patient's medical records.
Subfoveal choroidal neovascularisation (CNV) Clinical criteria: Treatment Phase: Initial treatment Treatment criteria: Must be treated by an ophthalmologist or by an accredited ophthalmology registrar in consultation with an ophthalmologist. The condition must be due to pathologic myopia (PM), AND The condition must be diagnosed by optical coherence tomography; OR The condition must be diagnosed by fluorescein angiography, AND The treatment must be the sole PBS-subsidised therapy for this condition. Authority approval for initial treatment of each eye must be sought. The first authority application for each eye must be made via the Online PBS Authorities System (real time assessment) or in writing via HPOS form upload or mail and must include: (1) Details (date, unique identifying number/code or provider number) of the optical coherence tomography or fluorescein angiogram report. If the application is submitted through HPOS form upload or mail, it must include: (a) details of the proposed prescription; and (b) a completed authority application form relevant to the indication and treatment phase (the latest version is located on the website specified in the Administrative Advice). All reports must be documented in the patient's medical records.
Curated subset. The full adverse-effect list is in the TGA Product Information; click any citation above to open it.